Introducing: Core Email Protection API in Threat Protection Workbench
Today, Proofpoint is expanding what API-based email security can deliver. Core Email Protection API is now available in Threat Protection Workbench, bringing full attack chain visibility and connected controls to organizations running Microsoft 365. For years, API-based email security has promised fast deployment, native M365 integration, and protection without changing mail flow. Those advantages remain. But the threat environment has changed, and speed alone is no longer enough.
In the agentic era, security teams need to know what was detected, why it was detected, who was targeted, how the attack behaved, where it may have spread, and what to do next. The detection verdict is only the beginning. The real advantage comes from understanding what the verdict means and acting before the blast radius expands. That requires an approach that’s complete and continuous with pre & post-delivery protection in a unified architecture.
The AI Threat Reality: Connected Attacks, Fragmented Defenses
With frontier AI, attackers have changed the clock. They no longer wait for a new vulnerability, a new exploit kit, or a slow-moving campaign cycle. They test, iterate, and relaunch. A single phishing campaign can now generate endless permutations of subject lines, senders, landing pages, attachments, and payloads, all at machine speed, all targeting the same organization.
The hard truth is that email remains the foundation of cyber defense, but email attacks do not stop at the inbox. A credential attack can begin in email, continue in a collaboration channel, and end with account takeover. A malicious link can be delivered to a user, shared into a team space, and revisited by an app or agent. AI helps attackers generate infinite variants of a single campaign across every channel simultaneously.
This is the new attack chain. And it is built to exploit the structural gaps that most defenses carry: no pre-delivery protections, supplier compromise blind spots, cloud and collaboration silos, and no account takeover controls to catch the step that follows credential theft.
On the operational side, the picture is just as difficult. Security teams face multiple consoles, siloed workflows, policy gaps between pre-delivery and post-delivery controls, and no unified view of a full attack campaign. Attackers plan in campaigns. Defenders investigate in incidents. That asymmetry is what makes the modern threat landscape so hard to close.
AI-accelerated threats amplify gaps In legacy defenses
What Core Email Protection API Delivers for Security Teams
Complete Attack Chain Visibility & Continuous Protection
In an era where attackers operate at machine speed, organizations need continuous protection that correlates threat intelligence, user behavior, and interaction signals across the full collaboration surface. Point-in-time controls that only see one stage of the attack are no longer suitable for today’s protection. Core Email Protection API is now a foundational protection to secure trusted interactions across email, messaging, collaboration apps, cloud apps, suppliers, customers, and AI-driven workflows against AI-scaled, multichannel attacks.
The Threat Interaction Map
The Threat Interaction Map gives SOC analysts immediate clarity on three questions: What was detected? Who was targeted? Are we at risk? Instead of waiting for manual investigation, analysts see an event summary with incident classification, impact, and resolution status; a visual map of how the attack unfolded and how it was resolved; validation against M365 Defender XDR for malware link clicks; and correlation with account takeover detection to confirm whether any accounts were compromised.
The Threat Interaction Map delivers instant clarity for SOC analysts investigating threats
Clear Explainability for Every Threat
Every condemned message comes with the reasoning behind the decision: behavioral patterns associated with known threat actors, sandboxing and detonation-level insights, and signals about unusual sender-recipient relationships. This visibility improves analyst confidence and reduces time spent validating whether the right decision was made.
Proofpoint explains the reasons an email was condemned, from behavior patterns to sandbox detonation insights.
Detecting Supplier Compromise
As organizations rely more heavily on suppliers, partners, and agentic workflows that exchange information across trusted domains, compromised supplier infrastructure becomes a higher-impact path into the business. Proofpoint surfaces the status of supplier domains so administrators can investigate, prioritize, and take action before a trusted relationship becomes an active attack vector.
Proofpoint identifies compromised supplier domains and surfaces the status to administrators.
Stopping Account Takeovers
In the agentic era, a compromised account is more than a compromised inbox. It can become a launch point into SaaS applications, sensitive workflows, delegated access, and automated actions. Proofpoint correlates unusual login behavior and suspicious SaaS changes back to related email compromise activity, giving analysts a clearer view of the full attack chain and enabling remediation including MFA reset, password reset, and other supported controls.
Proofpoint detects suspicious SaaS account activity, correlates it with email compromise signals, and supports rapid remediation.
Blocking Multi-Channel Attacks
When similar URLs appear in both email campaigns and collaboration tool messages, Proofpoint automatically correlates the activity into the same broader attack campaign. Instead of investigating each alert in isolation, analysts connect the chain. Protection applies at click time, before exposure, across messaging, collaboration tools, and browser-based workflows.
Proofpoint protects users from malicious links in messaging and browser-based interactions while correlating activity back to the broader campaign.
Agentic Response: The Satori Abuse Mailbox Agent
User-reported email is one of the highest-volume, highest-friction workflows in security operations. Satori Abuse Mailbox Agent drives manual review toward zero by automatically classifying reported messages, taking appropriate action, and closing the loop with end users. The result is a faster, more scalable abuse mailbox workflow that reduces analyst burden while improving response consistency and end-user trust.
Satori Abuse Mailbox Agent automatically classifies user-reported emails and closes the loop with end users.
Threat Landscape Reports
Threat Protection Workbench translates complex threat activity into focused reports across seven dimensions: People, Objectives, Actors, Effectiveness, Landscape, Organization, and BEC. Analysts get an immediate, customer-specific view of who is being attacked most, what threats surround them, and where protection or awareness actions are needed, without manual investigation and reporting work.
Proofpoint identifies Very Attacked People to show which users are most targeted and what threats they face.
Integration with the Broader Security Ecosystem
Core Email Protection API extends into the broader security ecosystem through integrations with CrowdStrike, Okta, Palo Alto Networks, and Microsoft Defender for Endpoint. By bringing identity activity, endpoint behavior, network telemetry, and messaging threats together, analysts can see how signals across tools relate to the same campaign, reducing manual tool switching and moving from isolated alerts to coordinated response.
The Detection Advantage Behind It All
Every email security vendor talks about detection. The difference is how fast protection is created, how much confidence the system carries, how clearly analysts can understand the verdict, and how quickly enforcement can happen.
Proofpoint’s detection advantage starts with speed from threat-seen to protection with threats seen across 2.9 million customers. When new threats appear, time matters. The faster a system can recognize malicious patterns, apply intelligence, and enforce protection, the less room attackers have to iterate. That is especially important as AI helps attackers generate new variants at scale.
It also comes from higher-conviction decisions. Modern attacks often combine signals that look weak in isolation: a newly observed sender, suspicious intent, supplier context, account behavior, message structure, brand impersonation, payload movement, or unusual interaction patterns. Proofpoint weighs those signals together, helping teams catch more threats faster while giving analysts more transparency into why something was stopped.
AI orchestrated to deliver 99.999% detection efficacy
Defense in Depth: Pre-Delivery and Post-Delivery, Together
Post-delivery API protection is powerful. It gives teams visibility into mailboxes, helps detect threats that appear after delivery, and enables rapid remediation when new intelligence emerges. For many organizations, it is a significant leap forward.
But mature security programs increasingly recognize that the strongest model combines post-delivery response with pre-delivery prevention, which reduces exposure before a user interacts with a malicious message. Together, they create defense in depth across the email lifecycle. When pre-delivery and post-delivery controls share detection intelligence, coordinate visibility, and support streamlined response, the result is stronger protection and a better operating model.
Continuous Protection for the AI Era: Pre-Delivery, Post-Delivery and Click Time Protection
With Core Email Protection API in Threat Protection Workbench, customers with both deployments get stronger protection for internal mail and multi-stage attacks, with investigation and response actions taken in one unified admin experience.
See It in Action
Learn how Proofpoint's helps organizations strengthen Microsoft 365 email security with advanced detection, rapid response, and API-based deployment in this in this solution brief.
And contact your Proofpoint account team for a live demo, and to understand how Proofpoint helps organizations move from email protection to end-to-end collaboration security.